Fluorinated cyclometalated iridium(iii) complexes as mitochondria-targeted theranostic anticancer agents
Author:
Affiliation:
1. MOE Key Laboratory of Bioinorganic and Synthetic Chemistry
2. School of Chemistry
3. Sun Yat-Sen University
4. Guangzhou 510275
5. P. R. China
Abstract
Cyclometalated iridium(iii) complexes bearing different numbers of fluorine atoms were developed to induce apoptosis via mitochondrial pathways and demonstrated much better anticancer activities than the widely used clinical chemotherapeutic agent cisplatin.
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/DT/C7DT01043E
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