Multicomponent encapsulation into fully degradable protein nanocarriers <i>via</i> interfacial azide–alkyne click reaction in miniemulsion allows the co-delivery of immunotherapeutics-Reference-Cited by-同舟云学术

Multicomponent encapsulation into fully degradable protein nanocarriers via interfacial azide–alkyne click reaction in miniemulsion allows the co-delivery of immunotherapeutics

Published:2022 Issue:8 Volume:7 Page:908-915
ISSN:2055-6756
Container-title:Nanoscale Horizons
language:en
Short-container-title:Nanoscale Horiz.

Author:

Hüppe Natkritta¹,Schunke Jenny²,Fichter Michael¹²,Mailänder Volker¹²,Wurm Frederik R.¹³^ORCID,Landfester Katharina¹^ORCID

Affiliation:

1. Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany

2. Department of Dermatology, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany

3. Sustainable Polymer Chemistry, Department of Molecules and Materials, Faculty of Science and Technology, MESA + Institute for Nanotechnology, University of Twente, Drienerlolaan 5, 7522 NB Enschede, The Netherlands

Abstract

Fully biodegradable protein nanocarriers were prepared by metal-free click reaction in inverse miniemulsion and loaded in situ with up to four different cargo molecules to achieve a synergistic therapeutic treatment.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NH/D2NH00243D

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1. Challenges in vaccination of neonates, infants and young children

2. Challenges for vaccination in the elderly

3. Vaccines for established cancer: overcoming the challenges posed by immune evasion