Hollow spherical nucleic acid structures based on polymer-coated phospholipid vesicles-Reference-Cited by-同舟云学术

Hollow spherical nucleic acid structures based on polymer-coated phospholipid vesicles

Published:2022 Issue:29 Volume:18 Page:5426-5434
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Haladjova Emi¹^ORCID,Petrova Maria²,Ugrinova Iva²,Forys Aleksander³^ORCID,Trzebicka Barbara³,Rangelov Stanislav¹^ORCID

Affiliation:

1. Institute of Polymers, Bulgarian Academy of Sciences, “Akad. G. Bonchev” St., Bl. 103-A, 1113 Sofia, Bulgaria

2. Institute of Molecular Biology, Bulgarian Academy of Sciences, “Akad. G. Bonchev” St., Bl. 21, 1113 Sofia, Bulgaria

3. Centre of Polymer and Carbon Materials, Polish Academy of Sciences, Marie Curie-Sklodowskiej 34, 41-819 Zabrze, Poland

Abstract

Oligonucleotide strands are grafted on the surface of polymer-coated phospholipid liposomes to produce hollow spherical nucleic acids. The constructs are able to bind complementary sequences and to enter cells without the need of transfection agents.

Funder

Bulgarian National Science Fund

Bulgarian Academy of Sciences

Polska Akademia Nauk

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SM/D2SM00355D

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