Synthetic chemistry fuels interdisciplinary approaches to the production of artemisinin-Reference-Cited by-同舟云学术

Synthetic chemistry fuels interdisciplinary approaches to the production of artemisinin

Published:2015 Issue:3 Volume:32 Page:359-366
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Corsello Michael A.¹²³⁴,Garg Neil K.¹²³⁴

Affiliation:

1. Department of Chemistry and Biochemistry

2. University of California

3. Los Angeles

4. USA

Abstract

In the developing world, multi-drug resistant malaria is an epidemic that claims the lives of 1–3 million people per year. Artemisinin, a naturally occurring small molecule, is a valuable weapon in the fight against this disease. This review highlights interdisciplinary efforts to access artemisinin, with an emphasis on the key role of synthetic chemistry.

Funder

Division of Graduate Education

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/NP/C4NP00113C

Reference59 articles.

1. Microbially Derived Artemisinin: A Biotechnology Solution to the Global Problem of Access to Affordable Antimalarial Drugs

2. Chloroquine‐Resistant Malaria

3. Guidelines for the treatment of malaria, World Health Organization, Geneva, 2nd edn, 2010