Synthesis, structural characterization and in vitro antiproliferative effects of novel organotin(iv) compounds with nicotinate and isonicotinate moieties on carcinoma cells

Author:

Vieriu Sabina-Mădălina12345ORCID,Someşan Adrian-Alexandru12345ORCID,Silvestru Cristian12345ORCID,Licarete Emilia67458ORCID,Banciu Manuela67458ORCID,Varga Richard A.12345ORCID

Affiliation:

1. Supramolecular Organic and Organometallic Chemistry Center

2. Department of Chemistry

3. Faculty of Chemistry and Chemical Engineering

4. Babeş-Bolyai University

5. Cluj-Napoca

6. Department of Molecular Biology and Biotechnology

7. Faculty of Biology and Geology

8. Romania

Abstract

Novel triorganotin(iv) nicotinates and isonicotinates were successfully synthesized and fully characterized. The preliminary results for their in vitro antiproliferative activity against the mouse colon carcinoma C26 cell line are also reported.

Funder

Universitatea Babeş-Bolyai

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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