An aryl-to-alkyl radical relay arylation reaction of a remote C(sp<sup>3</sup>)–H bond using 1,4-dicyanobenzene as an electrochemical redox-mediator-Reference-Cited by-同舟云学术

An aryl-to-alkyl radical relay arylation reaction of a remote C(sp³)–H bond using 1,4-dicyanobenzene as an electrochemical redox-mediator

Published:2024 Issue:15 Volume:11 Page:4182-4186
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Yu Weijie¹,Zhang Hongjie¹,Shen Zhipeng¹,Yang Lingyun¹,Luo Jin²^ORCID,Li Wendong¹,Zhao Kuang¹,Li Xiaolong¹,Xu Jiale¹,Zhou Yuan¹,Wang Tao¹^ORCID

Affiliation:

1. National Research Center for Carbohydrate Synthesis, Key Lab of Fluorine and Silicon for Energy Materials and Chemistry of Ministry of Education and Jiangxi Province Key Laboratory of Chemical Biology, Jiangxi Normal University, Nanchang 330022, Jiangxi, P. R. China

2. Analytical and Testing Center, Jiangxi Normal University, Nanchang, 330022, Jiangxi, P. R. China

Abstract

In this paper, we developed an electro-reductive aryl-to-alkyl radical relay arylation reaction of a remote C(sp3)–H bond via a 1,5-HAT process. This protocol features mild conditions, simple operation, and a broad substrate scope.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangxi Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D4QO00623B

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