Enantioselective organocatalytic Michael additions of N,N′-dialkylbarbituric acids to enones-Reference-Cited by-同舟云学术

Enantioselective organocatalytic Michael additions of N,N′-dialkylbarbituric acids to enones

Published:2017 Issue:40 Volume:15 Page:8669-8679
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Liu Ying¹²³⁴⁵,Zhang Yongna¹²³⁴⁵,Duan Hui-Xin¹²³⁴⁵,Wanyan Dong-Yan¹²³⁴⁵,Wang You-Qing¹²³⁴⁵^ORCID

Affiliation:

1. Provincial Key Laboratory of Polyoxometalate Chemistry

2. Provincial Key Laboratory of Natural Medicine and Immuno-Engineering

3. College of Chemistry and Chemical Engineering

4. Henan University

5. Kaifeng

Abstract

N,N′-Dialkylbarbituric acids as cyclic malonamide donors were successfully used in the organocatalytic asymmetric Michael additions with enones, affording the corresponding 5-substituted barbituric acid derivatives with 91–99% ee.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB02116J

Reference67 articles.

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5. Recent Advances in Asymmetric Organocatalytic 1,4‐Conjugate Additions

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