From mouth to gut: microfluidic <i>in vitro</i> simulation of human gastro-intestinal digestion and intestinal permeability-Reference-Cited by-同舟云学术

From mouth to gut: microfluidic in vitro simulation of human gastro-intestinal digestion and intestinal permeability

Published:2023 Issue:14 Volume:148 Page:3193-3203
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Xavier Miguel¹^ORCID,Rodrigues Patrícia M.¹²,Neto Mafalda D.¹^ORCID,Guedes Maria I.¹,Calero Victor¹^ORCID,Pastrana Lorenzo¹,Gonçalves Catarina¹^ORCID

Affiliation:

1. International Iberian Nanotechnology Laboratory, Avenida Mestre José Veiga, 4715-330 Braga, Portugal

2. University of Minho, Gualtar Campus, 4710-057 Braga, Portugal

Abstract

We present a novel microfluidic platform combining a Digestion-Chip and a Gut-Chip. The setup is able to simulate digestion and test digested samples in the cell-based Gut-Chip to evaluate intestinal permeability without compromising cell viability.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/AN/D2AN02088B

Reference43 articles.

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2. Organs-on-chips at the frontiers of drug discovery

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