Design and synthesis of eugenol/isoeugenol glycoconjugates and other analogues as antifungal agents against <i>Aspergillus fumigatus</i>-Reference-Cited by-同舟云学术

Design and synthesis of eugenol/isoeugenol glycoconjugates and other analogues as antifungal agents against Aspergillus fumigatus

Published:2022 Issue:8 Volume:13 Page:955-962
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Goswami Lakshmi¹²,Gupta Lovely³,Paul Sayantan¹²,Vermani Maansi³,Vijayaraghavan Pooja³,Bhattacharya Asish K.¹²^ORCID

Affiliation:

1. Division of Organic Chemistry, CSIR-National Chemical Laboratory (CSIR-NCL), Dr. Homi Bhabha Road, Pune, 411 008, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201 002, India

3. Antimycotic and Drug Susceptibility Laboratory, J3 Block, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Sector-125, Noida, India

Abstract

Design and synthesis of eugenol and isoeugenol based glycoconjugates and other analogous have been achieved using click chemistry. Two out of all the synthesized compounds exhibited significant antifungal activities against A. fumigatus.

Funder

Science and Engineering Research Board

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/MD/D2MD00138A

Reference40 articles.

1. The clinical spectrum of pulmonary aspergillosis

2. COVID-19 associated with pulmonary aspergillosis: A literature review