Supramolecular assembly of fluorogenic glyco-dots from perylenediimide-based glycoclusters for targeted imaging of cancer cells

Author:

Liu Ying12345,Ji Ding-Kun1234,Dong Lei678910,Galanos Nicolas678910,Zang Yi511121314,Li Jia511121314,Vidal Sébastien678910ORCID,He Xiao-Peng1234

Affiliation:

1. Key Laboratory for Advanced Materials & Institute of Fine Chemicals

2. East China University of Science and Technology

3. Shanghai 200237

4. P. R. China

5. National Center for Drug Screening

6. Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (UMR 5246)

7. Laboratoire de Chimie Organique 2 – Glycochimie

8. CNRS and Université Claude Bernard Lyon 1

9. F-69622 Villeurbanne

10. France

11. State Key Laboratory of Drug Research

12. Shanghai Institute of Materia Medica

13. Chinese Academy of Sciences

14. Shanghai 201203

Abstract

Supramolecular self-assembly between perylenediimide-based glycoclusters and a red-emitting fluorophore produces structurally uniform and stable glyco-dots amenable to targeted fluorogenic imaging of liver and triple-negative breast cancer cells.

Funder

China Scholarship Council

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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