IQCA-TASS: a nano-scaled P-selectin inhibitor capable of targeting thrombus and releasing IQCA/TARGD(S)S in vivo-Reference-Cited by-同舟云学术

IQCA-TASS: a nano-scaled P-selectin inhibitor capable of targeting thrombus and releasing IQCA/TARGD(S)S in vivo

Published:2017 Issue:5 Volume:5 Page:917-927
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Wu Jianhui¹²³⁴⁵^ORCID,Zhu Haimei¹²³⁴⁵^ORCID,Zhao Ming¹²³⁴⁵^ORCID,Wang Yuji¹²³⁴⁵^ORCID,Yang Guodong¹²³⁴⁵^ORCID,Wang Yaonan¹²³⁴⁵^ORCID,Zhao Shurui¹²³⁴⁵^ORCID,Gui Lin¹²³⁴⁵^ORCID,Zhang Xiaoyi¹²³⁴⁵^ORCID,Peng Shiqi¹²³⁴⁵^ORCID

Affiliation:

1. Beijing Area Major Laboratory of Peptide and Small Molecular Drugs

2. Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China

3. Beijing Laboratory of Biomedical Materials

4. College of Pharmaceutical Sciences

5. Capital Medical University

Abstract

Thrombosis is a serious threat to human health worldwide. Tetrahydroisoquinoline-3-carboxylic acid (IQCA) is an antithrombotic agent, while Thr-Ala-Arg-Gly-Asp(Ser)-Ser (TASS) can target thrombus.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TB/C6TB02705A

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