Enhancing the antitumor effect of methotrexate in intro and in vivo by a novel targeted single-walled carbon nanohorn-based drug delivery system-Reference-Cited by-同舟云学术

Enhancing the antitumor effect of methotrexate in intro and in vivo by a novel targeted single-walled carbon nanohorn-based drug delivery system

Published:2016 Issue:53 Volume:6 Page:47272-47280
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wang Ran¹²³⁴,Cui Hongjing¹²³⁴,Wang Junling¹²³⁴,Li Nannan¹²³⁴,Zhao Qian¹²³⁴,Zhou Ying¹²³⁴,Lv Zhiyi¹²³⁴,Zhong Wenying¹²³⁴⁵

Affiliation:

1. Department of Analytical Chemistry

2. China Pharmaceutical University

3. Nanjing

4. China

5. Department of Medicinal Chemistry

Abstract

The present research reports a smart multifunctional oxidized single-wall carbon nanohorns (oxSWNHs) drug delivery system (DDS) which could enhance the anti-tumor effect of methotrexate (MTX).

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA06667D

Reference49 articles.

1. Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase

2. Determining the cytotoxicity of methotrexate-loaded microemulsion on human breast, ovarian, and prostate carcinoma cell lines: a new modality for an old drug

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