Squeezed state in the hydrodynamic focusing regime for Escherichia coli bacteria detection

Author:

Zhao Wenhan12,Shang Xiaopeng2,Zhang Boran2ORCID,Yuan Dan3,Nguyen Binh Thi Thanh2,Wu Wenshuai2,Zhang Jing Bo2,Peng Niancai1,Liu Ai Qun24ORCID,Duan Fei5ORCID,Chin Lip Ket6ORCID

Affiliation:

1. Institute State Key Laboratory for Manufacturing Systems Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an, 710054, China

2. School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, Singapore

3. School of Mechanical and Mining Engineering, The University of Queensland, Brisbane 4072, Australia

4. Institute of Quantum Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR

5. School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798, Singapore

6. Department of Electrical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR

Abstract

A transition from the squeezed focusing state to the over-squeezed anti-focusing state when increasing the Reynolds number. The squeezed focusing state is critical for microfluidic cytometric analyses to maintain a high recovery rate.

Funder

City University of Hong Kong

Public Utilities Board - Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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