The first general synthesis of 2-C-(β-d-glycopyranosyl)pyrimidines and their evaluation as inhibitors of some glycoenzymes-Reference-Cited by-同舟云学术

The first general synthesis of 2-C-(β-d-glycopyranosyl)pyrimidines and their evaluation as inhibitors of some glycoenzymes

Published:2018 Issue:21 Volume:42 Page:17439-17446
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Szennyes Eszter¹²³⁴,Bokor Éva¹²³⁴,Langer Peter⁵⁶⁷⁸⁹^ORCID,Gyémánt Gyöngyi¹⁰²³⁴^ORCID,Docsa Tibor¹¹²¹²¹³⁴,Sipos Ádám¹¹²¹²¹³⁴,Somsák László¹²³⁴^ORCID

Affiliation:

1. Department of Organic Chemistry

2. University of Debrecen

3. Debrecen

4. Hungary

5. Department of Chemistry

6. University of Rostock

7. Albert-Einstein-Str. 3a

8. 18059 Rostock

9. Germany

10. Department of Inorganic and Analytical Chemistry

11. Department of Medical Chemistry, Faculty of Medicine

12. Egyetem tér 1

13. H-4032 Debrecen

Abstract

The first systematic study on the synthesis of 2-C-(β-d-glycopyranosyl)pyrimidines either from amidine A or glycosyl cyanides B and 1,3-dicarbonyl compounds.

Funder

European Regional Development Fund

Alexander von Humboldt-Stiftung

Nemzeti Kutatási, Fejlesztési és Innovációs Hivatal

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C8NJ04035D

Reference49 articles.

1. Discovery and design of carbohydrate-based therapeutics

2. Recent Advances in the Chemical Synthesis of C-Glycosides

3. Total Synthesis of Aryl C-Glycoside Natural Products: Strategies and Tactics

4. C-Glycopyranosyl Arenes and Hetarenes: Synthetic Methods and Bioactivity Focused on Antidiabetic Potential

5. C-Nucleosides: Synthetic Strategies and Biological Applications

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