ACE inhibitory peptides derived from de-fatted lemon basil seeds: optimization, purification, identification, structure–activity relationship and molecular docking analysis

Author:

Kheeree Norhameemee12345,Sangtanoo Papassara67345,Srimongkol Piroonporn67345,Saisavoey Tanatorn67345,Reamtong Onrapak8910115,Choowongkomon Kiattawee12213145ORCID,Karnchanatat Aphichart67345ORCID

Affiliation:

1. Program in Biotechnology

2. Faculty of Science

3. Chulalongkorn University

4. Bangkok 10330

5. Thailand

6. Research Unit in Bioconversion/Bioseparation for Value-Added Chemical Production

7. Institute of Biotechnology and Genetic Engineering

8. Department of Molecular Tropical Medicine and Genetics

9. Faculty of Tropical Medicine

10. Mahidol University

11. Bangkok 10400

12. Department of Biochemistry

13. Kasetsart University

14. Bangkok 10903

Abstract

The study determines optimized process conditions to maximize ACE inhibitory peptide production. The two novel hexa-peptides (LGRNLPPI and GPAGPAGL) from de-fatted lemon basil seeds (DLBS) was achieved.

Funder

Chulalongkorn University

Agricultural Research Development Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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