Studies on chemoselective synthesis of 1,4- and 1,2-dihydropyridine derivatives by a Hantzsch-like reaction: a combined experimental and DFT study
Author:
Affiliation:
1. Beijing Key Laboratory of Environmental and Viral Oncology
2. Faculty of Environment and Life
3. Beijing University of Technology
4. Beijing 100124
5. P. R. China
Abstract
In the experimental process of preparing 1,4-DHP by a Hantzsch-like reaction, it was found that a by-product named 1,2-DHP was produced.
Funder
Natural Science Foundation of Beijing Municipality
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/OB/D0OB02289F
Reference48 articles.
1. Synthesis, utility and medicinal importance of 1,2- & 1,4-dihydropyridines
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3. 1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells
4. Synthesis and anticoagulant activity of a new series of 1,4-dihydropyridine derivatives
5. Discovery of substituted 1,4-dihydroquinolines as novel promising class of P-glycoprotein inhibitors: First structure–activity relationships and bioanalytical studies
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