A significant role of non-thermal equilibrated electrons in the formation of deleterious complex DNA damage-Reference-Cited by-同舟云学术

A significant role of non-thermal equilibrated electrons in the formation of deleterious complex DNA damage

Published:2018 Issue:4 Volume:20 Page:2838-2844
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Kai Takeshi¹²³⁴^ORCID,Yokoya Akinari⁵⁶³⁴,Ukai Masatoshi⁷⁸⁹⁴,Fujii Kentaro⁵⁶³⁴,Toigawa Tomohiro¹²³⁴,Watanabe Ritsuko⁵⁶³⁴

Affiliation:

1. Nuclear Science and Engineering Center

2. Japan Atomic Energy Agency

3. Ibaraki

4. Japan

5. Quantum Beam Science Research Directorate

6. National Institutes for Quantum and Radiological Science and Technology

7. Department of Applied Physics

8. Tokyo University of Agriculture and Technology

9. Tokyo 184-8588

Abstract

Although most of the radiation damage to genomic DNA could be rendered harmless using repair enzymes in a living cell, a certain fraction of the damage is persistent resulting in serious genetic effects, such as mutation induction.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CP/C7CP06903K

Reference49 articles.

1. Initial Events in the Cellular Effects of Ionizing Radiations: Clustered Damage in DNA

2. DNA Damage Produced by Ionizing Radiation in Mammalian Cells: Identities, Mechanisms of Formation, and Reparability

3. Multiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIII

4. Clustered DNA Damage, Influence on Damage Excision by XRS5 Nuclear Extracts and Escherichia coli Nth and Fpg Proteins

5. DNA damage induced by the direct effect of radiation

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