Multimodal detection and analysis of a new type of advanced Heinz body-like aggregate (AHBA) and cytoskeleton deformation in human RBCs

Author:

Bulat Katarzyna1234,Dybas Jakub1234,Kaczmarska Magdalena1234,Rygula Anna5674,Jasztal Agnieszka1234,Szczesny-Malysiak Ewa1234,Baranska Malgorzata12348,Wood Bayden R.910111213ORCID,Marzec Katarzyna M.1234ORCID

Affiliation:

1. Jagiellonian Center for Experimental Therapeutics

2. Jagiellonian University

3. 30-348 Krakow

4. Poland

5. Laboratory of Analysis and Non-Destructive Investigation of Heritage Objects

6. National Museum in Kraków

7. 31-109 Krakow

8. Faculty of Chemistry

9. Centre for Biospectroscopy

10. School of Chemistry

11. Monash University

12. Clayton

13. Australia

Abstract

A new type of aggregate, formed in human red blood cells (RBCs) in response to glutaraldehyde treatment, was discovered and analyzed with the classical and advanced biomolecular imaging techniques.

Funder

Narodowe Centrum Badań i Rozwoju

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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