Chenopodium album metabolites act as dual topoisomerase inhibitors and induce apoptosis in the MCF7 cell line-Reference-Cited by-同舟云学术

Chenopodium album metabolites act as dual topoisomerase inhibitors and induce apoptosis in the MCF7 cell line

Published:2016 Issue:5 Volume:7 Page:837-844
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Chakraborty Debanjana¹²³⁴⁵,Jain Chetan Kumar⁶²³⁴⁵,Maity Arindam¹²³⁴⁵,Ghosh Shekhar¹²³⁴⁵,Choudhury Susanta Roy⁷⁸⁵,Jha Tarun⁹¹⁰¹¹⁵,Majumder Hemanta K.⁶²³⁴⁵,Mondal Nirup B.¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. Indian Institute of Chemical Biology

3. Council of Scientific and Industrial Research

4. Kolkata 700032

5. India

6. Molecular Parasitology Laboratory

7. Division of Research, Saroj Gupta Cancer Centre & Research Institute

8. Kolkata - 700 063

9. Department of Pharmaceutical Technology

10. Division of Medicinal and Pharmaceutical Chemistry

11. Kolkata-700 032

Abstract

Desgalactotigonin and oleanolic acid 3-O-β-d-glucuronide were isolated from Chenopodium album and were evaluated for cytotoxic activity against various cancer cell lines.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C5MD00502G

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