A new modified cytosine base capable of base pairing with guanine using four hydrogen bonds
Author:
Affiliation:
1. Department of Life Science
2. Tokyo Institute of Technology
3. Yokohama, 226-8501 Japan
Abstract
Oligonucleotides, containing 4-N-(1H-pyrrol-2-ylcarbonyl)deoxycytidine (dCPyc) and related derivatives, were synthesized via deprotection using 1.5 M NaOMe/MeOH.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/OB/C3OB42420K
Reference34 articles.
1. Tricyclic 2'-Deoxycytidine Analogs: Syntheses and Incorporation into Oligodeoxynucleotides Which Have Enhanced Binding to Complementary RNA
2. A Cytosine Analogue Capable of Clamp-Like Binding to a Guanine in Helical Nucleic Acids
3. Direct Observation of a Cytosine Analogue that Forms Five Hydrogen Bonds to Guanosine: Guanidino G-Clamp
4. Specific Fluorescent Probe for 8-Oxoguanosine
5. A Highly Fluorescent DNA Base Analogue that Forms Watson−Crick Base Pairs with Guanine
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