Investigating the complexation propensity of self-assembling dipeptides with the anticancer peptide-drug Bortezomib: a computational study-Reference-Cited by-同舟云学术

Investigating the complexation propensity of self-assembling dipeptides with the anticancer peptide-drug Bortezomib: a computational study

Published:2023 Issue:45 Volume:19 Page:8684-8697
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Divanach Peter¹²,Fanouraki Eirini¹²,Mitraki Anna¹²,Harmandaris Vagelis³⁴⁵^ORCID,Rissanou Anastassia N.³⁵⁶^ORCID

Affiliation:

1. Department of Materials Science and Technology, University of Crete, Voutes Campus Greece, Crete, Greece

2. Institute of Electronic Structure and Laser/Foundation for Research and Technology-Hellas, (FORTH), Nikolaou Plastira 100, Vassilika Vouton, Heraklion, Crete, Greece

3. Institute of Applied and Computational Mathematics (IACM), Foundation for Research and Technology Hellas, (FORTH), IACM/FORTH, GR-71110 Heraklion, Crete, Greece

4. Department of Mathematics and Applied Mathematics, University of Crete, GR-71409, Heraklion, Crete, Greece

5. Computation-based Science and Technology Research Center, The Cyprus Institute, Nicosia 2121, Cyprus

6. Theoretical & Physical Chemistry Institute, National Hellenic Research Foundation, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece

Abstract

The investigation of potential self-assembled peptides as carriers for the delivery of anticancer drug Bortezomib is the topic of the present study.

Funder

H2020 Spreading Excellence and Widening Participation

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SM/D3SM00930K

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1. Regulation of proteasome activity in health and disease

2. Bortezomib in Anti-Cancer Activity: A Potential Drug

3. Crystal Structure of the Boronic Acid-Based Proteasome Inhibitor Bortezomib in Complex with the Yeast 20S Proteasome