Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin
Author:
Affiliation:
1. School of Materials Science and Engineering
2. Gwangju Institute of Science and Technology (GIST)
3. Gwangju
4. Republic of Korea
Abstract
Human serum albumin (HSA) has been investigated as a serum half-life extender of therapeutic proteins thanks to its unusually long serum half-life.
Funder
National Research Foundation of Korea
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2018/BM/C8BM00456K
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5. The Major Histocompatibility Complex–related Fc Receptor for IgG (FcRn) Binds Albumin and Prolongs Its Lifespan
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