Computational study on NHC-catalyzed enantioselective and chemoselective fluorination of aliphatic aldehydes-Reference-Cited by-同舟云学术

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Computational study on NHC-catalyzed enantioselective and chemoselective fluorination of aliphatic aldehydes

Published:2017 Issue:10 Volume:4 Page:1987-1998
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wang Yang¹²³⁴,Qiao Yan⁵⁶⁷³⁴,Wei Donghui⁸⁹⁷³⁴^ORCID,Tang Mingsheng⁸⁹⁷³⁴

Affiliation:

1. Department of Material and Chemical Engineering

2. Zhengzhou University of Light Industry

3. Zhengzhou

4. P.R. China

5. Department of Pathophysiology

6. School of Basic Medical Sciences

7. Zhengzhou University

8. College of Chemistry and Molecular Engineering

9. Center of Computational Chemistry

Abstract

A mechanistic study on NHC-catalyzed enantioselective and chemoselective fluorination of aliphatic aldehydes has been performed for the first time.

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/QO/C7QO00436B

Reference77 articles.

1. Fluorine in Pharmaceuticals: Looking Beyond Intuition

2. Fluorine in medicinal chemistry

3. A New Approach towards the Asymmetric Fluorination of Alkenes Using Anionic Phase-Transfer Catalysts

4. Catalysis for fluorination and trifluoromethylation

5. Update 1 of: Asymmetric Fluorination, Trifluoromethylation, and Perfluoroalkylation Reactions

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