5-Fluoro-1,2,3-triazole motif in peptides and its electronic properties-Reference-Cited by-同舟云学术

5-Fluoro-1,2,3-triazole motif in peptides and its electronic properties

Published:2022 Issue:43 Volume:20 Page:8410-8414
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Laxio Arenas José¹,Retailleau Pascal²,Gillet Jean-Michel³^ORCID,Ghermani Nour-Eddine³⁴,Ongeri Sandrine¹,Crousse Benoît¹^ORCID

Affiliation:

1. UMR 8076, BioCIS, CNRS, Université Paris-Saclay, 92290 Châtenay-Malabry, France

2. Université Paris-Saclay, CNRS, Institut de Chimie des Substances Naturelles, 91198 Gif-sur-Yvette, France

3. UMR CNRS 8580, Ecole Centrale Paris, Grande Voie des Vignes, 92290 Châtenay-Malabry, France

4. UMR CNRS 8612, Université Paris-Saclay, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, 92296 Châtenay-Malabry, France

Abstract

The 5-fluoro triazole amino acid has been prepared by halogen exchange between the 5-iodo triazole and fluoride salts and incorporated in peptides. X-ray crystallography reveals a cylindrical shape in its deformation electron density.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB01716D

Reference26 articles.

1. A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

2. Ruthenium-Catalyzed Cycloaddition of Alkynes and Organic Azides

3. The growing impact of click chemistry on drug discovery

4. 1,2,3-Triazoles as Biomimetics in Peptide Science

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