Thermostable fatty acid hydroxylases from ancestral reconstruction of cytochrome P450 family 4 enzymes-Reference-Cited by-同舟云学术

Thermostable fatty acid hydroxylases from ancestral reconstruction of cytochrome P450 family 4 enzymes

Published:2024 Issue:15 Volume:14 Page:4211-4227
ISSN:2044-4753
Container-title:Catalysis Science & Technology
language:en
Short-container-title:Catal. Sci. Technol.

Author:

Harris Kurt L.¹,Zhang Yichi¹,Yang Jade²,Zeigler Maxwell B.²,Thomson Raine E. S.¹,Carrera-Pacheco Saskya E.³^ORCID,Russell Drake²^ORCID,Okada Shoko⁴,Strohmaier Silja J.¹,Gumulya Yosephine¹,Scott Colin⁴^ORCID,Totah Rheem A.²,Gillam Elizabeth M. J.¹^ORCID

Affiliation:

1. School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Brisbane, 4072, Australia

2. Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, WA, 98195-7631, USA

3. Centro de Investigación Biomédica (CENBIO), Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito 170527, Ecuador

4. CSIRO Synthetic Biology Future Science Platform, Black Mountain Science and Innovation Park, Clunies Ross St, Canberra, 2601, Australia

Abstract

Ancestral sequence reconstruction can be used to obtain highly thermostable catalysts of fatty acid hydroxylation.

Funder

Australian Research Council

Commonwealth Scientific and Industrial Research Organisation

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CY/D4CY00090K

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