An integrated microfluidic system for automatic detection of cholangiocarcinoma cells from bile-Reference-Cited by-同舟云学术

An integrated microfluidic system for automatic detection of cholangiocarcinoma cells from bile

Published:2024 Issue:2 Volume:24 Page:375-382
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Chang Jui-Lin¹,Huang Chien-Jui²,Tsai Yi-Cheng³,Chiang Nai-Jung⁴,Huang Yu-Shan²,Hung Shang-Cheng⁵^ORCID,Shan Yan-Shen²,Lee Gwo-Bin¹³⁶^ORCID

Affiliation:

1. Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu, Taiwan

2. Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan

3. Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan

4. Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan

5. Genomics Research Centre, Academia Sinica, Taipei, Taiwan

6. Institute of NanoEngineering and MicroSystems, National Tsing Hua University, Hsinchu, Taiwan

Abstract

An integrated microfluidic system to automate cholangiocarcinoma diagnosis from 1 mL bile was developed. In a single-blind test of 26 clinical samples, sensitivities and specificities of 100 and 83%, respectively, were documented.

Funder

National Science and Technology Council

National Health Research Institutes

National Tsing Hua University

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2024/LC/D3LC00862B

Reference39 articles.

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4. The utility of CA 19-9 in the diagnoses of cholangiocarcinoma in patients without primary sclerosing cholangitis

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