Syntheses of polypyridyl metal complexes and studies of their interaction with quadruplex DNA-Reference-Cited by-同舟云学术

Syntheses of polypyridyl metal complexes and studies of their interaction with quadruplex DNA

Published:2015 Issue:8 Volume:44 Page:3686-3700
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Stafford Verity S.¹²³⁴,Suntharalingam Kogularamanan¹²³⁴,Shivalingam Arun¹²³⁴,White Andrew J. P.¹²³⁴,Mann David J.⁵²³⁴,Vilar Ramon¹²³⁴

Affiliation:

1. Department of Chemistry

2. Imperial College London

3. London SW7 2AZ

4. UK

5. Department of Life Sciences

Abstract

A series of metal complexes with substituted terpyridines show high affinity towards quadruplex DNA, particularly bimetallic (trpy)Pt/M(cyclen) complexes.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/DT/C4DT02910K

Reference56 articles.

1. Tetramolecular Quadruplex Stability and Assembly

2. The G4 Genome

3. Existence and consequences of G-quadruplex structures in DNA

4. Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

5. G-quadruplex nucleic acids as therapeutic targets

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