A triple cascade approach towards the diastereoselective synthesis of spiro trans-decalinol scaffolds

Author:

Settipalli Poorna Chandrasekhar1,Anwar Shaik1ORCID

Affiliation:

1. Deparment of Chemistry, School of Applied Sciences and Humanities, Vignan's Foundation for Science Technology and Research-VFSTR (Deemed to be University), Vadlamudi-522 213, Guntur, Andhra Pradesh, India

Abstract

Multisubstituted spiro trans-decalinol scaffolds can be synthesized using readily accessible cyclohexanone and β-nitrostyrene with 2-arylidene-1,3-indanedione with a good yield (up to 75%) and high diastereoselectivity (>20 : 1) via (2+2+2) cyclization.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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