Sequestering survivin to functionalized nanoparticles: a strategy to enhance apoptosis in cancer cells-Reference-Cited by-同舟云学术

Sequestering survivin to functionalized nanoparticles: a strategy to enhance apoptosis in cancer cells

Published:2016 Issue:4 Volume:4 Page:614-626
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Jenkins Ragini¹²³⁴⁵,Bandera Yuriy P.¹²³⁴⁵,Daniele Michael A.¹²³⁴⁵,Ledford LeAnna L.⁶³⁴⁵,Tietje Ashlee⁷³⁴⁵,Kelso Andrew A.⁶³⁴⁵,Sehorn Michael G.⁶³⁴⁵,Wei Yanzhang⁷³⁴⁵,Chakrabarti Mrinmay⁸⁹¹⁰¹¹¹²,Ray Swapan K.⁸⁹¹⁰¹¹¹²,Foulger Stephen H.¹²³⁴⁵

Affiliation:

1. Center for Optical Materials Science and Engineering Technologies

2. Department of Materials Science & Engineering

3. Clemson University

4. Clemson

5. USA

6. Department of Genetics & Biochemistry

7. Department of Biological Sciences

8. Department of Pathology

9. Microbiology

10. & Immunology

11. University of South Carolina School of Medicine

12. Columbia

Abstract

Survivin belongs to the family of inhibitor of apoptosis proteins (IAP) and is present in most cancers while being below detection limits in most terminally differentiated adult tissues, making it an attractive protein to target for diagnostic and, potentially, therapeutic roles.

Funder

Directorate for Mathematical and Physical Sciences

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2016/BM/C5BM00580A

Reference83 articles.

1. Survivin, cancer networks and pathway-directed drug discovery

2. Control of apoptosis and mitotic spindle checkpoint by survivin

3. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

4. Validating survivin as a cancer therapeutic target

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