Synthesis of coenzyme A thioesters using methyl acyl phosphates in an aqueous medium
Author:
Affiliation:
1. Department of Biochemistry and Molecular Biology
2. Dalhousie University
3. Halifax, Canada
4. Department of Chemistry
Abstract
Regioselective S-acylation of coenzyme A is achieved under aqueous conditions using various aliphatic and aromatic carboxylic acids activated as their methyl acyl phosphate monoesters.
Funder
Natural Sciences and Engineering Research Council of Canada
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB02079K
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