Selected aryl thiosemicarbazones as a new class of multi-targeted monoamine oxidase inhibitors-Reference-Cited by-同舟云学术

Selected aryl thiosemicarbazones as a new class of multi-targeted monoamine oxidase inhibitors

Published:2018 Issue:11 Volume:9 Page:1871-1881
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Mathew Bijo¹²³⁴⁵^ORCID,Baek Seung Cheol⁶⁷⁸⁹,Grace Thomas Parambi Della²¹⁰¹¹¹²,Pil Lee Jae⁶⁷⁸⁹,Joy Monu¹³¹⁴¹⁵⁵^ORCID,Annie Rilda P. R.¹²³⁴⁵,Randev Rugma V.¹²³⁴⁵,Nithyamol P.¹²³⁴⁵,Vijayan Vijitha¹²³⁴⁵,Inasu Sini T.¹²³⁴⁵,Mathew Githa Elizabeth¹⁶¹⁷¹⁸⁵,Lohidakshan Krishnakumar K.²¹⁹²⁰⁵,Kumar Krishnan Girish²²¹²²⁵,Kim Hoon⁶⁷⁸⁹

Affiliation:

1. Division of Drug Design and Medicinal Chemistry Research Lab

2. Department of Pharmaceutical Chemistry

3. Ahalia School of Pharmacy

4. Palakkad-678557

5. India

6. Department of Pharmacy and Research Institute of Life Pharmaceutical Sciences

7. Sunchon National University

8. Suncheon-57922

9. Republic of Korea

10. Jouf University

11. Sakaka

12. Saudi Arabia

13. School of Pure & Applied Physics

14. M.G. University

15. Kottayam

16. Department of Pharmacology

17. Grace College of Pharmacy

18. Palakkad

19. Nirmala College of Health Science

20. Chalakudy-680311

21. College of Pharmaceutical Sciences

22. Government Medical College Trivandrum

Abstract

A series of 13 phenyl substituted thiosemicarbazones (SB1–SB13) were synthesized and evaluated for their inhibitory potential towards human recombinant monoamine oxidase A and B (MAO-A and MAO-B, respectively) and acetylcholinesterase.

Funder

Ministry of Education

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MD/C8MD00399H

Reference64 articles.

1. Enzymology of monoamine oxidase

2. Inhibitor Design for Monoamine Oxidases

3. Recent developments on the structure–activity relationship studies of MAO inhibitors and their role in different neurological disorders

5. Flavonoids: An Outstanding Structural Core for the Inhibition of Xanthine Oxidase Enzyme

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