Hydrophobicity may enhance membrane affinity and anti-cancer effects of Schiff base vanadium(v) catecholate complexes-Reference-Cited by-同舟云学术

Hydrophobicity may enhance membrane affinity and anti-cancer effects of Schiff base vanadium(v) catecholate complexes

Published:2019 Issue:19 Volume:48 Page:6383-6395
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Crans Debbie C.¹²³⁴⁵^ORCID,Koehn Jordan T.¹²³⁴^ORCID,Petry Stephanie M.¹²³⁴^ORCID,Glover Caleb M.¹²³⁴,Wijetunga Asanka⁶⁷⁸⁹,Kaur Ravinder⁶⁷⁸⁹,Levina Aviva⁶⁷⁸⁹^ORCID,Lay Peter A.⁶⁷⁸⁹^ORCID

Affiliation:

1. Chemistry Department

2. Colorado State University

3. Fort Collins

4. USA

5. Cell and Molecular Biology Program

6. School of Chemistry

7. The University of Sydney

8. Sydney

9. Australia

Abstract

Hydrophobicity may increase the hydrolytic stability of vanadium(v) catecholate complexes enabling rapid cellular uptake of the intact complex exhibiting potent anti-cancer activity.

Funder

University of Sydney

National Science Foundation

American Chemical Society

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/DT/C9DT00601J

Reference107 articles.