Synthesis and glycosidase inhibition of conformationally locked DNJ and DMJ derivatives exploiting a 2-oxo-C-allyl iminosugar-Reference-Cited by-同舟云学术

Synthesis and glycosidase inhibition of conformationally locked DNJ and DMJ derivatives exploiting a 2-oxo-C-allyl iminosugar

Published:2019 Issue:30 Volume:17 Page:7204-7214
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Foucart Quentin¹²³⁴⁵,Shimadate Yuna⁶⁷⁸⁹,Marrot Jérôme¹⁰¹¹¹²¹³¹⁴,Kato Atsushi⁶⁷⁸⁹^ORCID,Désiré Jérôme¹²³⁴⁵^ORCID,Blériot Yves¹²³⁴⁵^ORCID

Affiliation:

1. Université de Poitiers

2. IC2MP

3. UMR CNRS 7285

4. Equipe “Synthèse Organique”

5. Groupe Glycochimie

6. Department of Hospital Pharmacy

7. University of Toyama

8. Toyama 930-0194

9. Japan

10. Institut Lavoisier de Versailles

11. UMR-CNRS 8180

12. Université de Versailles

13. 78035 Versailles Cedex

14. France

Abstract

The synthesis and glycosidase inhibition profile of a series of bicyclic analogs of DNJ and DMJ displaying a similar hydroxyl pattern and a distinct conformation is described.

Funder

European Regional Development Fund

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB01402K

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