A rapid, sensitive colorimetric assay for the high-throughput screening of transaminases in liquid or solid-phase-Reference-Cited by-同舟云学术

A rapid, sensitive colorimetric assay for the high-throughput screening of transaminases in liquid or solid-phase

Published:2015 Issue:97 Volume:51 Page:17225-17228
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Baud D.¹²³,Ladkau N.¹²³,Moody T. S.⁴⁵⁶³,Ward J. M.⁷²³,Hailes H. C.¹²³

Affiliation:

1. Department of Chemistry

2. University College London

3. UK

4. Almac

5. Department of Biocatalysis and Isotope Chemistry

6. Craivagon

7. Department of Biochemical Engineering

Abstract

Red light for transaminases. A highly sensitive colorimetric assay using an inexpensive amine donor has been established for use in high-throughput transaminase screens.

Funder

Biotechnology and Biological Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C5CC06817G

Reference36 articles.

1. Biocatalytic Routes to Optically Active Amines

2. Recent achievements in developing the biocatalytic toolbox for chiral amine synthesis

3. Recent Developments of Cascade Reactions Involving ω-Transaminases

4. Enzymatic cascades for the regio- and stereoselective synthesis of chiral amines

5. Asymmetric Transfer Hydrogenation of Imines

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