Dual encapsulation of hydrophobic and hydrophilic drugs in PLGA nanoparticles by a single-step method: drug delivery and cytotoxicity assays-Reference-Cited by-同舟云学术

Dual encapsulation of hydrophobic and hydrophilic drugs in PLGA nanoparticles by a single-step method: drug delivery and cytotoxicity assays

Published:2016 Issue:112 Volume:6 Page:111060-111069
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Español Laura¹²³⁴,Larrea Ane⁵⁶⁷⁸⁹,Andreu Vanesa⁵⁶⁷⁸⁹,Mendoza Gracia⁵⁶⁷⁸⁹,Arruebo Manuel⁵⁶⁷⁸⁹^ORCID,Sebastian Victor⁵⁶⁷⁸⁹,Aurora-Prado María S.¹²³⁴,Kedor-Hackmann Erika R. M.¹²³⁴,Santoro Maria Ines R. M.¹²³⁴,Santamaria Jesus⁵⁶⁷⁸⁹

Affiliation:

1. Faculty of Pharmaceutical Sciences

2. University of Sao Paulo

3. 05508-000 Sao Paulo

4. Brazil

5. Department of Chemical Engineering

6. Aragon Institute of Nanoscience (INA)

7. University of Zaragoza

8. 50018 Zaragoza

9. Spain

Abstract

Dual drug encapsulation in biodegradable nanoparticles is always challenging and often requires strenuous optimization of the synthesis–encapsulation processes.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA23620K

Reference61 articles.

1. Polymeric Nanoparticles for Drug Delivery

2. Development and physicochemical characterization of dexamethasone-loaded polymeric nanocapsule suspensions

3. Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

4. Dual Drug Release from Core–Shell Nanoparticles with Distinct Release Profiles

5. Dual agents loaded PLGA nanoparticles: Systematic study of particle size and drug entrapment efficiency

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