Photochemical bromination and iodination of peptides and proteins by photoexcitation of aqueous halides

Author:

Luo Pan12,Liu Zheyi1,Zhang Tingting12,Wang Xiaolei13,Liu Jing4,Liu Yiqiang23,Zhou Xiaohu23,Chen Yang23,Hou Guangjin5ORCID,Dong Wenrui3ORCID,Xiao Chunlei3,Jin Yan1,Yang Xueming3ORCID,Wang Fangjun12ORCID

Affiliation:

1. CAS Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China

2. University of Chinese Academy of Sciences, Beijing 100049, China

3. State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China

4. College of Pharmacy, Dalian Medical University, Dalian, 116044, China

5. State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China

Abstract

Laser excitation of aqueous halides at wavelengths shorter than 200 nm for structure-selective photochemical halogenation of native proteins.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Liaoning Province

National Key Research and Development Program of China

Chinese Academy of Sciences

Dalian Institute of Chemical Physics

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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