para-Aminosalicylic acid in the treatment of manganese toxicity. Complexation of Mn2+ with 4-amino-2-hydroxybenzoic acid and its N-acetylated metabolite

Author:

Lachowicz Joanna Izabela12345ORCID,Nurchi Valeria Marina12345ORCID,Crisponi Guido12345ORCID,Cappai Ilaria12345ORCID,Cappai Rosita12345,Busato Matteo67895ORCID,Melchior Andrea67895ORCID,Tolazzi Marilena67895ORCID,Peana Massimiliano1011125ORCID,Garribba Eugenio1011125ORCID,Zoroddu Maria Antonietta1011125ORCID,Coni Pierpaolo132345ORCID,Pichiri Giuseppina132345ORCID,Aaseth Jan1415161718ORCID

Affiliation:

1. Dipartimento di Scienze Chimiche e Geologiche

2. Università di Cagliari

3. Cittadella Universitaria

4. I-09042 Monserrato

5. Italy

6. DPIA

7. Laboratorio di Scienze e Tecnologie Chimiche

8. Università di Udine

9. 33100 Udine

10. Dipartimento di Chimica e Farmacia

11. Università di Sassari

12. 07100 Sassari

13. Dipartimento di Scienze Chirurgiche

14. Department of Public Health

15. Hedmark University College

16. Elverum

17. Norway

18. Department of Internal Medicine

Abstract

Manganese excess can induce in humans neurological disorders known as manganism.

Funder

Ministero dell'Istruzione, dell'Università e della Ricerca

Fondazione Banco di Sardegna

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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