Surface nanotopography and cell shape modulate tumor cell susceptibility to NK cell cytotoxicity-Reference-Cited by-同舟云学术

Surface nanotopography and cell shape modulate tumor cell susceptibility to NK cell cytotoxicity

Published:2023 Issue:10 Volume:10 Page:4532-4540
ISSN:2051-6347
Container-title:Materials Horizons
language:en
Short-container-title:Mater. Horiz.

Author:

Cho Yongbum¹,Kim JangHyuk²,Park Jeehun³,Doh Junsang²³⁴^ORCID

Affiliation:

1. School of Interdisciplinary Bioscience and Bioengineering (I-Bio), Pohang University of Science and Technology, 77, Cheongam-ro, Pohang, Gyeongbuk, 37673, Republic of Korea

2. Department of Materials Science and Engineering, Seoul National University, Seoul, South Korea

3. SOFT Foundry Institute, Seoul National University, Seoul, South Korea

4. Institute of Engineering Research, BioMAX, Seoul National University, Seoul, South Korea

Abstract

The roles of surface nanotopography and tumor cell morphologies in NK cell cytotoxicity were studied using micro/nanofabrication technology. These findings will be useful for the development of immune cell-based solid tumor treatments.

Funder

National Research Foundation of Korea

Seoul National University

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/MH/D3MH00367A

Reference61 articles.

1. Natural Killer Cells in Cancer Immunotherapy

2. Functions of natural killer cells

3. Concepts of extracellular matrix remodelling in tumour progression and metastasis

4. The tumor microenvironment

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