Reactions of β-diketone compounds with nitriles catalyzed by Lewis acids: a simple approach to β-enaminone synthesis-Reference-Cited by-同舟云学术

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Reactions of β-diketone compounds with nitriles catalyzed by Lewis acids: a simple approach to β-enaminone synthesis

Published:2014 Issue:109 Volume:4 Page:63897-63900
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Cheng Xu¹²³⁴⁵,Pei Shuchen¹²³⁴⁵,Xue Chenchen¹²³⁴⁵,Cao Kaifei⁶⁷⁸,Hai Li¹²³⁴⁵,Wu Yong¹²³⁴⁵

Affiliation:

1. Key Laboratory of Drug Targeting and Drug Delivery System of Education Ministry

2. Department of Medicinal Chemistry

3. West China School of Pharmacy

4. West China Hospital

5. Sichuan University

6. Clinical Medicine School

7. Chengdu University of Traditional Chinese Medicine

8. Chengdu, P. R. China

Abstract

Aluminium chloride selectively promoted the nucleophilic attack of β-diketone compounds with nitriles to give enaminones.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA10879E

Reference47 articles.

1. Recent development in preparation reactivity and biological activity of enaminoketones and enaminothiones and their utilization to prepare heterocyclic compounds

2. Synthesis and anticonvulsant activity of enaminones Part 7. Synthesis and anticonvulsant evaluation of ethyl 4-[(substituted phenyl)amino]-6-methyl-2-oxocyclohex-3-ene-1-carboxylates and their corresponding 5-methylcyclohex-2-enone derivatives

3. Enaminones as building blocks in heterocyclic synthesis: New syntheses of nicotinic acid and thienopyridine derivatives

4. Synthesis and anticonvulsant activity of enaminones

5. Synthesis and anticonvulsant activity of enaminones. 2. Further structure-activity correlations

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