Ketoreductase catalyzed stereoselective bioreduction of α-nitro ketones-Reference-Cited by-同舟云学术

Ketoreductase catalyzed stereoselective bioreduction of α-nitro ketones

Published:2019 Issue:14 Volume:17 Page:3575-3580
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wang Zexu¹²³⁴⁵,Wu Xiaofan⁶⁷⁸⁵,Li Zhining¹²³⁴⁵,Huang Zedu¹²³⁴⁵^ORCID,Chen Fener¹²³⁴⁵

Affiliation:

1. Engineering Center of Catalysis and Synthesis for Chiral Molecules

2. Department of Chemistry

3. Fudan University

4. Shanghai

5. P. R. China

6. College of Chemical Engineering

7. Fuzhou University

8. Fuzhou

Abstract

Stereocomplementary bioreduction of 33 α-nitro ketones catalyzed by ketoreductases (KREDs) with publicly known sequences furnished both enantiomers of β-nitro alcohols.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB00051H

Reference29 articles.

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