Photoredox-catalyzed unsymmetrical diamination of alkenes for access to vicinal diamines

Author:

Liu Jie1,Guo Lu2,Chen Zhang1,Guo Yu1ORCID,Zhang Wei1,Peng Xue1,Wang Zhen13ORCID,Zeng Yao-Fu1ORCID

Affiliation:

1. School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China

2. Department of Sports Medicine, Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China

3. MOE Key Lab of Rare Pediatric Diseases, University of South China, Hengyang, Hunan, 421001, China

Abstract

Unsymmetrical vicinal diamines have been achieved via the photoredox-catalyzed difunctionalization of alkenes by using N-aminopyridinium salts and nitriles as the amination reagents, respectively.

Funder

National Natural Science Foundation of China

Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study

Publisher

Royal Society of Chemistry (RSC)

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