Ultrasensitive detection of transcription factors with a highly-efficient diaminoterephthalate fluorophore via an electrogenerated chemiluminescence strategy

Author:

Fan Zhenqiang12345,Wang Jianfeng12345ORCID,Hao Nan6789,Li Yihao12345,Yin Yuhang12345,Wang Zepeng12345,Ding Yuedi1011121314,Zhao Jianfeng12345ORCID,Zhang Kai1011121314ORCID,Huang Wei12345

Affiliation:

1. Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM)

2. Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM)

3. Nanjing Tech University (NanjingTech)

4. Nanjing 211816

5. China

6. School of Chemistry and Chemical Engineering

7. Jiangsu University

8. Zhenjiang

9. P. R. China

10. Key Laboratory of Nuclear Medicine

11. Ministry of Health

12. Jiangsu Key Laboratory of Molecular Nuclear Medicine

13. Jiangsu Institute of Nuclear Medicine

14. Wuxi

Abstract

Herein, we apply electrogenerated chemiluminescence (ECL) based method employing diaminoterephthalate analogue as ECL emitter and hairpin DNA as amplification strategy, for sensitive assay of transcription factors.

Funder

Natural Science Foundation of Jiangsu Province

Key Medical Subjects of Jiangsu Province

Major State Basic Research Development Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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