New transition metal complexes containing imidazole rings endowed with potential antiamoebic activity-Reference-Cited by-同舟云学术

New transition metal complexes containing imidazole rings endowed with potential antiamoebic activity

Published:2016 Issue:5 Volume:7 Page:982-989
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Wani Mohmmad Younus¹²³⁴⁵,Bhat Abdul Roouf⁶⁷⁸⁴,Azam Amir⁶²³⁴,Athar Fareeda¹²³⁴,Sobral Abilio J. F. N.⁵⁹¹⁰¹¹¹²

Affiliation:

1. Centre for Interdisciplinary Research in Basic Sciences

2. Jamia Millia Islamia (Central University)

3. New Delhi-110025

4. India

5. Departamento de Quımica

6. Department of Chemistry

7. S. P. College

8. Srinagar-190001

9. FCTUC

10. Universidade de Coimbra, Rua Larga

11. 3004-535 Coimbra

12. Portugal

Abstract

Imidazole-hydrazones were found to be better antiamoebic lead molecules compared to the standard drug metronidazole (MNZ). Chelation of these bioactive ligands with metals enhanced their activity profiles.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00013D

Reference42 articles.

1. Protozoan genomes: gene identification and annotation

2. Amoebiasis

3. Amebiasis

4. Probing the antiamoebic and cytotoxicity potency of novel tetrazole and triazine derivatives

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