The synthesis of pharmacologically important oxindoles <i>via</i> the asymmetric aldol reaction of isatin and the investigation of the organocatalytic activity of new alicyclic β-amino acid derivatives-Reference-Cited by-同舟云学术

The synthesis of pharmacologically important oxindoles via the asymmetric aldol reaction of isatin and the investigation of the organocatalytic activity of new alicyclic β-amino acid derivatives

Published:2023 Issue:28 Volume:13 Page:19356-19365
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Faragó Tünde¹^ORCID,Remete Attila M.¹,Szatmári István¹²^ORCID,Ambrus Rita³,Palkó Márta¹^ORCID

Affiliation:

1. Institute of Pharmaceutical Chemistry, University of Szeged, Eötvös utca 6, Szeged H-6720, Hungary

2. Stereochemistry Research Group, Eötvös Loránd Research Network, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary

3. Institute of Pharmaceutical Technology and Regulatory Affairs Faculty of Pharmacy, University of Szeged, Eötvös utca 6, Szeged H-6720, Hungary

Abstract

This work involves the synthesis and subsequent development of a number of novel organocatalysts generated from β-amino acids bearing diendo and diexo norbornene skeletons to improve their catalytic characteristics.

Funder

Emberi Eroforrások Minisztériuma

Nemzeti Kutatási, Fejlesztési és Innovaciós Alap

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA03528J

Reference46 articles.

1. 3-Substituted-3-hydroxy-2-oxindole, an Emerging New Scaffold for Drug Discovery with Potential Anti-Cancer and other Biological Activities

2. Screening of simple N-aryl and N-heteroaryl pyrrolidine amide organocatalysts for the enantioselective aldol reaction of acetone with isatin