Synthesis of barbituric acid containing nucleotides and their implications for the origin of primitive informational polymers-Reference-Cited by-同舟云学术

Synthesis of barbituric acid containing nucleotides and their implications for the origin of primitive informational polymers

Published:2016 Issue:30 Volume:18 Page:20144-20152
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Mungi Chaitanya V.¹²³⁴,Singh Sachin Kumar⁵²³⁴,Chugh Jeetender¹²³⁴⁵,Rajamani Sudha¹²³⁴

Affiliation:

1. Department of Biology

2. Indian Institute of Science Education and Research (IISER)

3. Pune

4. India

5. Department of Chemistry

Abstract

Nucleotides containing barbituric acid were synthesized and polymerized under prebiotically relevant conditions. This study demonstrates the plausibility of the emergence of primitive informational polymers from ribonucleotides with alternate heterocycles.

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CP/C6CP00686H

Reference22 articles.

1. Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions

2. Studies in prebiotic synthesis

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4. Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism

5. Asphalt, Water, and the Prebiotic Synthesis of Ribose, Ribonucleosides, and RNA

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