Balancing fluorescence and singlet oxygen formation in push–pull type near-infrared BODIPY photosensitizers

Author:

Deckers Jasper123ORCID,Cardeynaels Tom1234ORCID,Doria Sandra56,Tumanov Nikolay7ORCID,Lapini Andrea58,Ethirajan Anitha29ORCID,Ameloot Marcel10ORCID,Wouters Johan7,Di Donato Mariangela56ORCID,Champagne Benoît4ORCID,Maes Wouter123ORCID

Affiliation:

1. UHasselt – Hasselt University, Institute for Materials Research (IMO), Design & Synthesis of Organic Semiconductors (DSOS), Agoralaan, 3590 Diepenbeek, Belgium

2. IMEC, Associated Lab IMOMEC, Wetenschapspark 1, 3590 Diepenbeek, Belgium

3. Energyville, Thorpark, 3600 Genk, Belgium

4. UNamur – University of Namur, Namur Institute of Structured Matter, Theoretical and Structural Physical Chemistry Unit, Laboratory of Theoretical Chemistry (LTC), Rue de Bruxelles 61, 5000 Namur, Belgium

5. European Laboratory for Non-Linear Spectroscopy (LENS), Via Nello Carrara 1, 50019 Sesto Fiorentino (FI), Italy

6. Instituto di Chimica dei Composti OrganoMetallici (ICCOM-CNR), Via Madonna Del Piano 10, 50019 Sesto Fiorentino (FI), Italy

7. UNamur – University of Namur, Namur Medicine and Drug Innovation Center (NAMEDIC), Namur Research Institute for Life Sciences (NARILIS), Namur Institute of Structured Matter (NISM), Rue de Bruxelles 61, 5000 Namur, Belgium

8. Department of Chemistry, Life Science and Environmental Sustainability, University of Parma, Parco Area delle Scienze, 17/A, 43124 Parma, Italy

9. UHasselt – Hasselt University, Institute for Materials Research (IMO), Nano-Biophysics and Soft Matter Interfaces (NSI), Wetenschapspark 1, 3590 Diepenbeek, Belgium

10. UHasselt – Hasselt University, Biomedical Research Institute (BIOMED), Agoralaan, 3590 Diepenbeek, Belgium

Abstract

Rational, computationally guided, molecular design affords push–pull BODIPY photosensitizers with balanced brightness and phototoxicity for image-guided photodynamic therapy.

Funder

Horizon 2020 Framework Programme

Université de Namur

Universiteit Hasselt

Fonds Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry

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