Synthesis of a tetrasaccharide and its glycoconjugate corresponding to the capsular polysaccharide of Neisseria meningitidis serogroup X and its immunochemical studies-Reference-Cited by-同舟云学术

Synthesis of a tetrasaccharide and its glycoconjugate corresponding to the capsular polysaccharide of Neisseria meningitidis serogroup X and its immunochemical studies

Published:2015 Issue:52 Volume:5 Page:41332-41340
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Harale Kishore R.¹²³,Dumare Nilesh B.¹²³,Singh Deepti¹²³,Misra Anup Kumar⁴⁵⁶³,Chhikara Manoj Kumar¹²³

Affiliation:

1. MSD Wellcome Trust Hilleman Laboratories Pvt. Ltd.

2. New Delhi 110062

3. India

4. Bose Institute

5. Division of Molecular Medicine

6. Kolkata 700054

Abstract

A tetrameric unit of capsular polysaccharide of Neisseria meningitidis X has been synthesized and conjugated with tetanus toxoid. Their immunochemical property has been evaluated which indicates towards the development of a potential MenX vaccine.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA02993G

Reference37 articles.

1. Epidemic meningitis, meningococcaemia, and Neisseria meningitidis

2. Meningococcal Disease

3. Advances in the Development of Vaccines againstNeisseria meningitidis

4. Population genetics and molecular epidemiology ofNeisseria meningitidis

5. Impact of the Serogroup A Meningococcal Conjugate Vaccine, MenAfriVac, on Carriage and Herd Immunity

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