Rationalisation of a mechanism for sensing single point variants in target DNA using anthracene-tagged base discriminating probes-Reference-Cited by-同舟云学术

Rationalisation of a mechanism for sensing single point variants in target DNA using anthracene-tagged base discriminating probes

Published:2018 Issue:35 Volume:16 Page:6576-6585
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Duprey Jean-Louis H. A.¹²³⁴,Bassani Dario M.⁵⁶⁷⁸^ORCID,Hyde Eva I.⁹¹⁰³⁴^ORCID,Jonusauskas Gediminas¹¹¹²⁶⁷⁸^ORCID,Ludwig Christian¹³¹⁴¹⁵²³,Rodger Alison¹⁶¹⁷¹⁸¹⁹²⁰^ORCID,Spencer Neil¹²³⁴,Vyle Joseph S.²¹²²²³⁴,Wilkie John¹²³⁴,Zhao Zheng-Yun¹²³⁴,Tucker James H. R.¹²³⁴^ORCID

Affiliation:

1. School of Chemistry

2. University of Birmingham

3. Edgbaston

4. UK

5. Institut des Sciences Moléculaires, CNRS UMR 5255

6. Université Bordeaux

7. Talence 33405

8. France

9. School of Biosciences

10. The University of Birmingham

11. Laboratoire Ondes et Matière d'Aquitaine

12. UMR CNRS 5798

13. Henry Wellcome Building for Biomolecular NMR Spectroscopy

14. Institute of Cancer & Genomic Sciences

15. College of Medical & Dental Sciences

16. Department of Molecular Sciences

17. Faculty of Science and Engineering

18. Macquarie University

19. North Ryde

20. Australia

21. School of Chemistry and Chemical Engineering

22. Queen's University Belfast

23. Belfast

Abstract

The fluorescence sensing mechanism for identifying single base changes in target DNA strands has been established through detailed biophysical measurements.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01710G

Reference73 articles.

1. Chemistry Challenges in SNP Typing

2. Progress and promise in understanding the genetic basis of common diseases

3. The butterfly effect in cancer: A single base mutation can remodel the cell