“On water” synthesis of dibenzo-[1,4]-diazepin-1-ones using l-proline as an organocatalyst and under catalyst-free conditions, and their evaluation as α-glucosidase inhibitors
Author:
Affiliation:
1. Department of Chemistry
2. National Institute of Technology
3. Warangal-506 004
4. India
5. Department of Biotechnology
Abstract
Functionalized dibenzo-[1,4]-diazepin-1-ones are synthesized using the “on-water” concept in the presence of l-proline (organocatalyst; 20 mol%) and under catalyst free conditions (sealed tube) in an aqueous medium.
Funder
Science and Engineering Research Board
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2017/NJ/C7NJ01021D
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5. Homobivalent Ligands of the Atypical Antipsychotic Clozapine: Design, Synthesis, and Pharmacological Evaluation
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