Synergistic applications of cyclodextrin-based systems and metal–organic frameworks in transdermal drug delivery for skin cancer therapy

Author:

Scattolin Thomas1ORCID,Tonon Giovanni2,Botter Eleonora2,Canale Viviana Claudia3ORCID,Hasanzadeh Mahdi4ORCID,Cuscela Denise Maria56,Buschini Annamaria56,Zarepour Atefeh7,Khosravi Arezoo8ORCID,Cordani Marco910,Rizzolio Flavio1112ORCID,Zarrabi Ali1314ORCID

Affiliation:

1. Dipartimento di Scienze Chimiche, Università degli studi di Padova, via Marzolo 1, 35131, Padova, Italy

2. Dipartimento di Scienze Molecolari e Nanosistemi, Università Ca’ Foscari, Campus Scientifico Via Torino 155, 30174, Venezia-Mestre, Italy

3. Department of Chemical Science and Technologies, University of Rome ‘Tor Vergata’, Via della Ricerca Scientifica, 00133 Rome, Italy

4. Department of Textile Engineering, Yazd University, P.O. Box 89195-741, Yazd, Iran

5. Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11/A, 43124 Parma, Italy

6. COMT (Interdepartmental Centre for Molecular and Translational Oncology), University of Parma, Parco Area delle Scienze 11/A, 43124 Parma, Italy

7. Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai–600 077, India

8. Department of Genetics and Bioengineering, Faculty of Engineering and Natural Sciences, Istanbul Okan University, Istanbul 34959, Turkey

9. Department of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid 28040, Spain

10. Instituto de Investigaciones Sanitarias San Carlos (IdISSC), Madrid 28040, Spain

11. Pathology Unit, Centro di Riferimento Oncologico di Aviano (C.R.O.) IRCCS, Aviano, Italy

12. Department of Molecular Sciences and Nanosystems, Ca' Foscari University of Venice, Venice, Italy

13. Department of Biomedical Engineering, Faculty of Engineering and Natural Sciences, Istinye University, Istanbul 34396, Turkey

14. Graduate School of Biotechnology and Bioengineering, Yuan Ze University, Taoyuan 320315, Taiwan

Abstract

This review article explores the innovative field of eco-friendly cyclodextrin-based coordination polymers and metal–organic frameworks (MOFs) for transdermal drug delivery in the case of skin cancer therapy.

Publisher

Royal Society of Chemistry (RSC)

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